Team's Article

Polyphenols are a group of plant-based chemicals that have at least one phenol group. One broad type of polyphenols are phenolic acids including red fruits, black radishes, onions, coffees, cereals and spices.The second broad group are the flavonoids, anthocyanidins found in berries and wine, flavones found in herbs, flavonols found in broccoli, tomato and tea, flavanones found in citrus fruits and juices, and flavan-3-ols found in cocoa, tea and wine. Finally, some famous ones don't fit into any class, including resveratrol and stilbenes from wine and nuts, curcumin in spices, and lignans in flax seeds.

Polyphenols will improve your health in many ways:

    Lowering cholesterol
    Lowering blood pressure
    Found to reduce plaque in arteries
    Improve artery (endothelial) function
    Prevent platelet clumping
    Improve arterial flexibility
    Improved life span
    Improves your complexion
    Awesome anti-ageing effect around your facial tissue
    Greatly Improves energy and well-being
    Improved libido (sex drive)

An Apple A Day Keeps the Doctor Away

Based on the high procyanidin content of apples, which also contain a unique polyphenol known as phloridzin, modern science is now confirming the truth of this old adage. Yoko Akazome, PhD, chief researcher at the Fundamental Research Laboratory in Asahi Breweries, Ltd. in Japan, shared with Life Extension some of his recent research on apple polyphenols.

In healthy volunteers, apple polyphenols not only lower blood cholesterol, but also inhibit triglyceride absorption,without any apparent ill-effects. Animal studies confirm the anti-obesity effect of apple polyphenols via beneficial effects on fat metabolism and insulin sensitivity.

By combating high cholesterol and obesity, apple polyphenols are a good defense against heart disease and diabetes. A randomized, placebo-controlled study in 71 moderately overweight volunteers showed that those taking an apple polyphenol capsule for 12 weeks had reduction in central body fat covering the abdominal organs and improvements in fat metabolism, with no adverse effects.

In addition, apple polyphenols have the potential to reduce allergic conditions46 by blocking the release of histamine (an irritating substance causing inflammation and itching) from the mast cells that mediate allergic reactions.

Even better news is that these anti-allergic effects in the laboratory translate into clinical improvements in patients with atopic dermatitis, an allergic skin condition; and in persistent allergic rhinitis, or hayfever, based on the results of a rigorous, placebo-controlled study. Even in high doses, apple polyphenols have no toxic effects.

Studies by other groups show that the anti-inflammatory and antioxidant qualities of apple polyphenols have a wide range of other health benefits, including protection of colon cells against free-radical damage that could cause cancer,5 prevention of bone loss in an experimental model of menopausal osteoporosis, decreased lipid oxidation, and cholesterol reduction. Population studies have linked increased consumption of apples with lower risk of some cancers, cardiovascular disease, asthma, and diabetes.


Polyphenols: Healing Compounds From Nature’s Pharmacy

The top 10 foods containing high concentrations of Polyphenol are:
    Cloves
    Star anise
    Cocoa powder
    Mexican oregano

    Dried celery seed
    Black chokeberry
    Dark chocolate
    Flaxseed meal
    Black elderberry
    Chestnut

Notable mentions also for, pomegranate, grapes, citrus's, rosemary, thyme, spearmint, capers, basil, curry, sage, blueberries, red wine, coffee and strawberries.


The evidence for the heart benefits for foods rich in polyphenols comes from hundreds of studies. One example published last year was a large study in Europe reporting that a higher intake of polyphenols, particularly stilbenes from grapes and nuts and lignans (yes some are beneficial) from flax, was associated with a longer life span



For those who require more scientific information on this matter. The path to your "enlightenment" about Polyphenols starts by clicking here  The Database URL: http://www.phenol-explorer.eu

Ohta Y, Sami M, Kanda T, Saito K, Osada K, Kato H. Gene expression analysis of the anti-obesity effect by apple polyphenols in rats fed a high fat diet or a normal diet. J Oleo Sci. 2006;55(6):305-14. Ohta Y, Funayama M, Seino H, et al. Apple polyphenol improves lipid metabolism and insulin independence in obese rats. Nippon Shokuhin Kagaku Kogaku Kaishi. 2007;54(6):287-94.  Osada K, Suzuki T, Kawakami Y, et al. Dose-dependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterol. Lipids. 2006 Feb;41(2):133-9. Nagasako-Akazome Y, Kanda T, Ohtake Y, Shimasaki H, Kobayashi T. Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index. J Oleo Sci. 2007;56(8):417-28. Akiyama H, Sakushima J, Taniuchi S, et al. Antiallergic effect of apple polyphenols on the allergic model mouse. Biol Pharm Bull. 2000 Nov;23(11):1370-3. Kanda T, Akiyama H, Yanagida A, et al. Inhibitory effects of apple polyphenol on induced histamine release from RBL-2H3 cells and rat mast cells. Biosci Biotechnol Biochem. 1998 Jul;62(7):1284-9. Tokura T, Nakano N, Ito T, et al. Inhibitory effect of polyphenol-enriched apple extracts on mast cell degranulation in vitro targeting the binding between IgE and FcepsilonRI. Biosci Biotechnol Biochem. 2005 Oct;69(10):1974-7. Enomoto T, Nagasako-Akazome Y, Kanda T, Ikeda M, Dake Y. Clinical effects of apply polyphenols on persistent allergic rhinitis: A randomized double-blind placebo-controlled parallel arm study. J Investig Allergol Clin Immunol. 2006;16(5):283-9. Akazome Y. Characteristics and physiological functions of polyphenols from apples. Biofactors. 2004;22(1-4):311-4. Kojima T, Akiyama H, Sasai M, et al. Anti-allergic effect of apple polyphenol on patients with atopic dermatitis: A pilot study. Allergol Int. 2000:49(1):69-73. Schaefer S, Baum M, Eisenbrand G, Janzowski C. Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines. Mol Nutr Food Res. 2006 Apr;50(4-5):413-7. Puel C, Quintin A, Mathey J, et al. Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions. Calcif Tissue Int. 2005 Nov;77(5):311-8. Boyer J, Liu RH. Apple phytochemicals and their health benefits. Nutr J. 2004 May 12;35



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